I. They are man-made proteins. 

II. They stimulate immunological function due to their ability to bind to specific antigens. 

III. They are used in treating viral infections like that of Nipah virus. 

Which of the statements given above are correct? 

(a) I and II only 

(b) II and III only 

(c) I and III only 

(d) I, II and III

Ans-d

Explanation

‘Mono’ means ‘one’ and ‘clone’ means ‘identical copy’. Monoclonal antibodies are identical copies of one type of antibody.

The production of monoclonal antibodies is an in vitro process by the use of tissue-culture techniques.

Hence statement 1 is correct 

Antibodies are proteins produced by a type of white blood cell called a lymphocyte. Pathogens have proteins on their surface called antigens. When a pathogen infects the body, the lymphocytes recognise these antigens as foreign and attack them by producing antibodies.

Antibodies bind to specific antigens on pathogens. This means that only one type of antibody will bind to a matching antigen.

Hence statement 2 is correct 

Monoclonal antibodies, as a highly effective immunotherapeutic treatment against viral infections, are now widely used for pre- or postexposure protection against infectious diseases caused by highly virulent and lethal viruses, such as Ebola virus (EBOV)and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and Nipah virus (NiV)

NiV41 and NiV42 – Two neutralising antibodies (NiV41 and NiV42) targeting the NiV receptor binding protein (RBP) were identified. antibodies derived from NiV41 display cross-reactivity against both NiV and Hendra virus (HeV), whereas the antibody based on NiV42 is only specific to NiV. 

Hence statement 3 is correct

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